1. error while loading shared libraries: libXp.so.6 solve method : yum install libXp 2. An error status was returned by the program 'xsetup', the X Window System version of 'install'. The following messages were written to standard error: /tmp/27387tmwinstall/update/bin/glnxa64/xsetup: error while loading shared libraries: libmwins.so: cannot open shared object file: No such file or directory The reason is the install program of SELinux and MATLAB conflict. As SELinux the MAC enforce control need some call of glibc library which will also be used by Matlab. So the method is shutdown the SELinux before install matlab： # setenforce 0 #just shutdown for a while U can also modify /etc/selinux/config SELINUX = disabled #disable it forever 3. If U can not install in GUI, you can use character mode install, the command is： ./install* -t   PS. sometimes the install script maybe have not the excute property , U should chmod +x install first..   Good Luck.